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Original Article Semaphorin-3F functions as a tumor suppressor in colorectal cancer due to regulation by DNA methylation

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Academic year: 2020

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Figure

Figure 1. SEMA3F expression in CRC tissues and adjacent non-tumor tissues. A: Representative result of SEMA3F protein expression in six matched samples of CRC tissues (T) and adjacent non-tumors tissues (N)
Figure 2. Down-regulation of SEMA3F in CRC cells is associated with DNA methylation of SEMA3F gene promoter region
Figure 3. The effect of SEMA3F on cell migration and colony formation. A and B: Cell migration was measured by transwell assay, which indicated that overexpression of SEMA3F inhibited cell migration in SW620 cell line
Figure 4. Effect of 5-Aza-CdR on SW620 cell invasion and colony formation. A-C: Comparison of SEMA3F mRNA expression by qRT-PCR and western blot analysis in SW620 cell line after treatment with 5-Aza-CdR (5 or 10 μM)

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