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Atrial fibrillation risk loci interact to modulate Ca2+ dependent atrial rhythm homeostasis

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Academic year: 2020

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Figure

Figure 1. Gata4 Gata4irregular atrial electrogram, consistent with lack of transcription factors haploinsufficiency rescues atrial arrhythmias caused by Tbx5 haploinsufficiency
Figure 2. Abnormal atrial cardiomyocyte electrical activity caused by Tbx5larization events (EADs and DADs) observed in atrial myocytes
Figure 3. Antagonistic interactions between TBX5 and GATA4 on Atp2a21-way ANOVA followed by Tukey post-hoc test
Figure 4. Reduced SERCA function caused by Tbx5SR load. Removal of caffeine in the absence of external Nao provides a measure of SERCA2-mediated SR calcium uptake
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