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Evaluation of Polymethine Dyes as Potential Probes for Near Infrared Fluorescence Imaging of Tumors: Part - 1

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Figure

Figure 1: Absorption (A), fluorescence (B) spectra of near infrared fluorophores (NIRFs) 1-4 and ICG in methanol (5 µM)
Figure 2:   Absorption (A) and fluorescence (B) spectra of fluorophores 5, 7 and 8 derived from the cyanine dye IR820 in methanol (5µM)
Figure 4:  A single diode laser with an excitation at 785 nm and an emission at 820 nm long pass (LP) was used to determine the NIR flow uptake of dyes ICG, IR820, 1–10, and 6 (cypate)
Figure 5:  NIR whole body fluorescence images of BALB/c mice bearing Colon 26 tumors at 24 h post injection (p.i.) of the fluorophores 1-3 (dose: 0.03µmol/kg)
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