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The Activation of ATR in Response to Double-Stranded DNA Breaks

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Figure

Figure 1:  CtIP associates with DSB-containing chromatin
Figure 2:  CtIP interacts in a regulated manner with TopBP1 in Xenopus egg extracts
Figure 3:  The BRCT I-II region of TopBP1 is necessary and sufficient for association with CtIP
Figure 4:  Multiple Effects of ISWI Depletion from Interphase Extracts (A) One microliter of extracts treated with control-IgG or anti-ISWI antibodies from two successive rounds of depletion
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