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Emerging treatment options for myelofibrosis: focus on pacritinib

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Figure

Table 1 Primary myelofibrosis: Dupriez, IPSS, and DIPSS scoring algorithms
Table 2 Primary myelofibrosis: DIPSS-Plus scoring algorithm
Figure 1 JAK/STAT pathway and potential therapeutic targets.Abbreviations: DNA, deoxyribonucleic acid; EPO, erythropoietin; IL, interleukin; JAK, Janus kinase; PI3K, phosphoinositide 3-kinase; P*, phosphorylation; MAPK, mitogen-activated protein kinase; mTOR, mammalian target of rapamycin; SOCS, suppressor of cytokine signaling; STAT, signal transducer and activator of transcription; TNF, tumor necrosis factor.
Figure 2 Molecular structure of pacritinib.
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