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Shan, Bing (2010): The novel sumoylation enhancer RSUME is implicated in pituitary tumor pathogenesis. Dissertation, LMU München: Fakultät für Biologie

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Academic year: 2020

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Figure

Figure 2. The SUMO conjugation pathway. SUMO is synthesized as a precursor and processed by hydrolases to make the carboxy-terminal double-glycine motif available for conjugation
Figure 3. Functions of sumoylation. Some of the known functions of sumoylation are indicated
Figure 4. Actions of RSUME on the sumoylation process. RSUME enhances Ubc9-
Figure 6. Oxygen-dependent regulation of HIF-1 stabilization and transactivation. In normoxia (left), two proline residues of HIF-1 (P402 and P564) and asparagine (N803) are hydroxylated by PHDs and FIH-1, respectively, in an O2, 2-OG, and Fe2+-dependent
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