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The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer

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Academic year: 2020

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Figure

Figure 1: Celecoxib inhibited cell proliferation in ovarian cancer cell lines. The SKOV3, Hey and IGROV1 cells were cultured for 24 hours and then treated with celecoxib at indicated doses in 96 well plates for 72 hours
Figure 2: Celecoxib induced cell cycle G1 arrest and apoptosis in ovarian cancer cells lines
Figure 3: Celecoxib inhibited cell adhesion and invasion in ovarian cancer cells lines
Figure 4: Celecoxib inhibited tumor growth in a genetically engineered mouse model of serous ovarian cancer (KpB mouse model).was palpated, these mice underwent treatment with celecoxib (5 mg/kg) versus placebo for 4 weeks
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