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Investigating Structure Function Relationships in Ion Channels Using Unnatural Amino Acids

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Figure

Figure 1.1. An illustration of signals traveling through nerve cells in the brain.
Figure 1.4. Views of the Na+ channel. A) Topology of a voltage-gated Na+ channel. Na+ channels are
Figure 1.5. Views of the nAChR. A) An illustration of the pentameric channel. B) Each subunit has a
Figure 1.6. Unnatural mutagenesis allows for more subtle alteration in the structure of an amino acid such
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a and b both prior to the dCA coupling reaction and after the unreacted portion was recovered from the dCA coupling reaction, since these two points would reflect the

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