• No results found

Unexpected complexity in the interference activity of a cloned influenza defective interfering RNA

N/A
N/A
Protected

Academic year: 2020

Share "Unexpected complexity in the interference activity of a cloned influenza defective interfering RNA"

Copied!
16
0
0

Loading.... (view fulltext now)

Full text

Loading

Figure

Fig. 1 a. Schematic diagram of influenza segment 1244 DI RNA (1/244), segment 2265 DI RNA (2/265), segment 3262 DI RNA (3/262), and the Seg 1-GFPRNA expressed from plasmids
Table 1 Sequences of the primers used in this study. The primers containing mixed nucleotides were designed for detection ofboth A/PR8 and A/WSN-derived RNAs
Fig. 2 Detection of RNAs synthesised by 1/244 DI RNA and 1/244 KO DI RNA by Northern blot and primer extension and protection of mice frominfluenza
Fig. 3 Effect of increasing amounts of DI and full-length genome segment RNAs on expression of GFP from a segment 1 reporter gene construct.cells (top) were transfected with an empty vector (1fected plasmids expressing 1/244 DI, 1/244 KO DI, 3/262 DI, full
+5

References

Related documents

The present study reveals a second form of host resistance, based on the observation that mice of certain strains fail to develop tumors following radiation and virus challenge..

Copyright and reuse: City Research Online aims to make research outputs of City, University of London available to a wider audience.. Copyright and Moral Rights remain with

The inward flow of technological knowledge from a firm’s partners first increases and then decreases with the share of novel partners in the firm’s R&D partnership

Reasons for community pharmacists not participating in research include a lack of time, 33 – 41 expertise, 25 26 28 monetary reimbursement, 27 prioritisa- tion and management

RNA templates derived from chimeric constructs containing increasing amounts of viral 3 9 NCR sequence were analyzed to further map the cis-acting elements required for rotavirus

Consistent with our observation that the HIV-1 p6 domain encompasses a virion association motif for Vpr, the presence both of a p6 domain and of a Vpr-like gene product is a

There is also evidence that the defects in murine leukemia virus expression were of viral origin and that infected clones produced viruses which could not form plaques in cell

We consider two perturbations in the deterministic SIS model and formulate the original model as a stochastic differential equation with two cor- related Brownian motions for the