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Discovery of selective, antimetastatic and anti cancer stem cell metallohelices via post assembly modification

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Figure

Fig. 1Metallohelix architecturesshow clean conversion of (a)the absolute consinglets via asymmetric self-assembly and CuAAC
Table 1Cell viability (IC50 mean values, mM) of the investigated compounds. Cell survival was evaluated using the MTTa assay
Fig. 3Antiproliferative selectivity indices of triplex metallohelices for cancercancer cell line/cancer cell line), IC vs
Fig. 5Time-dependent cellular response pro(B)0.125in arbitrary units is a measure of cell sensor impedance: (A)files of A2780 cancer cells treated with increasing concentrations of the metallohelices; cell index D-[Fe2L13]Cl4 (lines: orange – 4 mM; green –
+3

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