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Generation of pattern and form in the developing limb

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Figure

Fig. 1. Chick wing and leg pattern.Note that the shape of the limb bud is the same at this stage for both the wing and leg.and dorso-ventral (DV), polarizing region at the posterior margin is shown in white.of development) with major axes depicted: antero-
Fig. 2. underlying mesenchyme, which forms a meshwork of cells. Adapted from Todt and Fallonnote the presence of intercellular spaces in the ectoderm away from the apex; also in thewhereas the overlying periderm is composed of flattened cells in a continuo
Fig. 3. Classical disggregration/reaggregation experiment in thechick wing.unpatterned forearm elements and digits that are often reduced inwing bud resumes outgrowth resulting in a wing with a humerus, butthen grafted to a host embryo to continue developm
Fig. 4. tional values is associated with missing anterior elements (434*). Aster-posterior expansion to accommodate the full range of opposing posi-(4322*3*4*).(234)

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