Friday, December 7, 2012
Instructional presentations
Basics of biomechanics and cross-linking Chair: G. Kymionis
09:00 Basics of cross-linking Spoerl, Eberhard (Germany) invited
09:15 Fluence, illumination time and beam profile Mrochen, Michael (Switzerland) 09:30 Biomechanics of the cornea Kling, Sabine (Spain) invited
09:45 Discussion
10:00–10:30 Coffee break
Using diagnostic devices Chair: J. Frucht-Pery
10:30 Corneal Topography and the ERSS score, an update Randleman, Brad (USA) 10:45 Scheimpflug topography Ambrosio, Renato (Brazil) invited
11:00 Discussion
11:30-12:45 Lunch
Established & new indications, patient selection Chair: D. Epstein, G. Kymionis
12:45 Keratoconus, PMD and iatrogenic keratectasia Gaster, Ronald (USA) invited
13:00 CXL with / following refractive laser surgery Kymionis, George (Greece) invited
13:15 Indications for CXL in adults and children Frucht-Pery, Joseph (Israel) invited
13:30 Transepithelial CXL – fiction and reality Raiskup, Frederik (Germany) invited
13:45 Predicting factors of visual acuity improvement after CXL Vinciguerra, Paolo (Italy) invited
14:00 Discussion
Company Courses (Open for all participants)
14:15–15:00 SOOFT Italy: Iontophoresis: the definitive CXL Chair: P. Vinciguerra
What we know today about ocular iontophoresis Joseph Frucht-Pery Transepithelial CXL: current technique and future directions David 0' Brart Evaluation of riboflavin distribution induced by corneal Franccis Malecaze iontophoresis and effects on collagen fibers after Myriam Cassagne iontophoresis + UV-A irradiation
Structural modifications and tissue response after current Leonardo Mastropasqua transepithelial CXL vs iontophoretic transepithelial CXL Mario Nubile
Histological analysis after CXL via iontophoresis: overall Rita Mencucci evaluation on epithelium, stroma and endothelium
Comparative stress-strain measurements of human corneas Paolo Vinciguerra after transepithelial UV-A induced CXL: impregnation with
15:00 – 15:45 Avedro: New Science, New Applications Chair: David Muller Accelerated Cross-Linking Safety John Marshall, PhD New Cross-linking Science Marc Friedman, PhD Trans-epithelial cross-linking with ParaCel Peter Hersh, MD Lasik Xtra and AK Xtra John Kanellopoulos, MD The Future David Muller, PhD
15:45 – 16:15 Coffee break
16:15 – 17:00 Peschke Meditrade
Crosslinking for infectious Keratitis THEN - Now – FUTURE Jes Mortensen 17:00 – 17:45 IROC Innocross: Update from the innovator of CXL Chair. M. Mrochen
The IROC INNOCROSS Product Range John Mc Master
The treatment protocol with the UV-X 2000 Victor Derhartunian, MD 6 month clinical data with the UV-X 2000 Arthur Cummings, MD A brief update on the ORA David Taylor
17:45 – 18:30 Short communications Chair: B. Randleman Basic
17:45-17:50 Effect of Higher Intensity Corneal Cross-Linking (CXL) In-Vitro using Second Harmonic (SH) Optical Microscopy. (A-41)
McQuaid, Rebecca (Ireland) 17:50-17:55 Keratoconus corneal Architecture after cross-linking by
riboflavin/UVA - Ultrastructural studies. (A-33)
Akhtar, Saeed (Saudi Arabia) 18:00-18:05 The Effect of Riboflavin/UVA Collagen Cross-linking on Stromal
Ultrastructure and Fluid Dynamics. (A-12)
Hayes, Sally (Great Britain)
Clinical
18:05-18:10 Consensus on reporting parameters for scleral and corneal biomechanical measurements. (A-51)
Richoz, Olivier (Switzerland) 18:10-18:15 Evaluation of Keratoconus Match Index and Keratoconus Match
Probability in the Diagnosis of Forme Fruste Keratoconus. (A-40)
Gatzioufas, Zisis (Germany) 18:15-18:20 Results of the personalized krosslinking treatment of
keratoektazies. (A-25)
Anisimov, Sergei I. (Russia) 18:20-18:25 Intra and Inter-observer variability of measurements with
Pentacam HR® in patients with mild to moderate keratoconus. (A-68)
Majo, François (Switzerland) 18:25-18:30 A new protocol for treatment of severe infectious keratitis:
Corneal Collagen Cross-Linking Window Absorption (CXL –WA). (A-17)
Rosetta, Pietro (Italy) 18:30-18:35 Characteristics Influencing Outcomes of Corneal Collagen
Crosslinking for Keratoconus and Corneal Ectasia: Development of a Patient Treatment Algorithm. (A-2)
Hersh, Peter (United States) 18:35-18:40 Refractive Cross Linking. The next generation of keratorefractive
procedure (A-46)
El Hage, Sami (United States)
Posters
Posters will be displayed in the main meeting room during the conference Poster 1 (A-7)
UV collagen Cross-Linking in paediatric age Fortunato, Michele (Italy)
Poster 2 (A-79)
Assessment of accelerated Collagen Cross-Linking for the treatment of refractory bacterial keratitis in dogs and cats (8 cases)
Frank Famose (Switzerland)
Poster 3 (A-13)
Transepithelial CXL and standard CXL: a comparative morfological study throught confocal microscopy and OCT anterior segment
Gabbriellini, Giovanna (Italy)
Poster 4 (A-14)
Keratotensotopography - new diagnostic possibilities for studying the biomechanical properties of the cornea duiring CXL
Anisimov, Sergey (Russia)
Poster 5 (A-16)
Corneal cross-linking as a treatment for keratoconus: Four-year morphological and clinical outcomes with respect to patient age.
Vinciguerra, Riccardo (Italy)
Poster 7 (A-24)
The study of the morphological changes in the cornea after krosslinking conducted in experiment Zolotorevskiy, Kirill A. (Russia)
Poster 8 (A-26)
Pockmarked transepithelial crosslinking for keratoconus: one-year results Rechichi, Miguel (Italy)
Poster 9 (A-27)
Results of progressive hyperopic shift correction by сombined local corneal crosslinking in patients after radial keratotomy
Kalinnikov, Yurii (Russia)
Poster 10 (A-29)
Transepithelial PTK for “Epithelium OFF” topo-guided CXL. Kovalov, Andriy (Ukraine)
Poster 11 (A-35)
Histological changes in eye-banked human corneas after standard and high intensity cross-linking with riboflavin and UV-A
Poster 12 (A-36)
Zernicke Values as a Measure of Collagen Crosslinking Effectiveness Saponara, Fiorella (United States)
Poster 13 (A-44)
Collagen Crosslinking in progressive Keratoconus – 5 years follow-up Constantin Mihaela Monica & Corbu Catalina (Romania)
Poster 15 (A-47)
Comparison of Laser-Assisted Removal of Epithelium to Mechanical Debridement in Corneal Cross-Linking for Progressive Keratoconus: 6-Month Results
Gaster, Ronald (United States)
Poster 17 (A-53)
Effect of collagen cross-linking on the limbal stem cells. Richoz, Olivier (Switzerland)
Poster 18 (A-58)
Modification of collagen cross-linking parameters for the treatment of acanthamoeba keratitis Richoz, Olivier (Switzerland)
Poster 19 (A-61)
LASEK+CXL in Keratoconic patients Borissova, Jenny (Bulgaria)
Poster 20 (A-65)
Combined Alcohol-Assisted Topography-guided Phototherapeutic Keratectomy and Accelerated Corneal Collagen Cross-Linking for Pellucid Marginal Degeneration
Aoyama, Masaru (Japan)
Poster 21 (A-66)
Corneal morphological changes of corneal collagen crosslinking in Canada Al-Ghoul, Ahmed (Canada)
Poster 22 (A-72)
Treatment of cornea hydrops with UV cross linking Geerards, Annette (Netherlands)
Poster 23 (A-74)
Biomechanical analysis on the effect of permanent myopia reduction by following trans-epithelial Crosslinking with Ortho-K
Saturday, December 8, 2012
Scientific program
08:10-08:15 Introductory remarks and welcome Hafezi, Farhad (Switzerland)
Basic research
Chair: E. Spoerl, K. Meek08:15-08:30 Corneal shape supported by collagen organization Meek, Keith (UK) invited
08:30-08:45 Corneal biomechanics, age-related changes Elsheikh , Ahmed (UK) invited
08:45-09:00 Corneal biomechanics, hormonal influences Gatzioufas, Zisis (Switzerland)
invited
09:00-09:15 Biomechanical changes in standard and rapid CXL Schumacher, Silvia (Switzerland)
invited
09:15-09:30 Spatially depth-resolved corneal elasticity: applications to CXL Kling, Sabine (Spain) invited
09.30-09:45 Corneal Biomechanical Properties at Different CXL-Fluences (A-43)
Richoz, Oliver (Switzerland) 09:45-10:00 Determination of the excimer laser ablation rate in previously
cross-linked cornea. (A-49)
Alba Mosquera, S. (Germany) 10:00-10:15 Discussion
10:15-10:30 Light for Sight Hafezi, Nikki & Hafezi, Farhad (Switzerland)
10:30-11:00 Coffee break
Translational research
Chair: F. Majo, M. Mrochen11:00-11:10 Rapid CXL and LASIK Seiler, Theo (Switzerland) invited
11:10-11:20 Comparative Stress Strain and Histological Measurements Of Human Corneas After UV-A Induced Cross-linking:
Impregnation With Iontophoresis, Different Riboflavin Solutions And Irradiance Power
Vinciguerra, Paolo (Italy) invited
11:20-11:25 ”Corneal Crosslinking and iontophoresis: Biomechanical and histological ex vivo study.” (A-60)
Mastropasqua, Leonardo (Italy) 11:25-11:30 Combining Iontophoreis and CXL: a basic study on human
corneas. (A-28)
Mencucci, Rita (Italy) 11:30-11:40 Long-term impact of CXL upon corneal permeability in a live
rabbit model. (A-55)
Stewart, Jay (USA) 11:40-11:50 Discussion
Clinical research
Chair: P. Vinciguerra, B. Randleman13:00-13:10 Irradiation profiles Koller, Tobias (Switzerland) Invited
13:10-13:17 Epithelial Remodeling after Corneal Collagen Cross-linking Evaluated by Spectral-domain OCT. (A-78)
Randleman, J. Bradley (USA) 13:17-13:24 UV-A absorption rate of fluorescein and its impact on the
efficacy of collagen cross-linking (CXL) for infectious corneal melting. (A-50)
Richoz, Olivier (Switzerland) 13:24-13:31 Corneal collagen crosslinking in advanced keratoconus with
ultra-thin corneas. (A-62)
Wajnsztajn, Denise (Israel) 13:31-13:38 Is corneal collagen crosslinking effective in the treatment of
advanced keratoconus? (A-63)
Cagil, Nurullah (Turkey) 13:38-13:45 Two Years Results of Topo-guided PRK after ICR segments
implantation and corneal collagen crosslinking in a three-step procedure for keratoconus. (A-76)
Coskunseven, Efekan (Turkey) 13:45-13:52 Safety and Efficacy of High-Fluence CXL for Progressive
Keratoconus; Short-Term Results (A-42)
Richoz, Olivier (Switzerland) 13:52-13:59 Reduction of femtosecond astigmatic keratotomy (fsAK)
regrassion with combined simultaneous high fluence CXL (hfCXL). A novel refractive procedure
Kanellopoulos, John (Greece) 13:59-13:06 Analysis of Keratoconus using Keratoconus Prediction Index
and Cone Location & Magnitue Index. (A-48)
Ramani, Veera (Malaysia) 14:06-14:30 Discussion
14:30-15:00 Coffee break
Recommendation
Chair: F. Hafezi, P. Rosetta1) Recommendations on CXL in children
15:00-15:20 Decision making and outcome of CXL in children Frucht-Pery, Joseph (Israel)
2) Reporting results – are we comparing apples to oranges? Finding a consensus on reporting outcomes
15.20-15:25 Refraction? Seiler, Theo (Switzerland) invited
15:25-15:30 Epithelial map? Randleman, J. Bradley (USA) 15:30-15:35 Keratokonus indices? Ambrosio, Renato (Brazil) invited
15:35-15:40 Kmax? Reporting the error Mrochen, Michael (Switzerland) 15:40-16:00 Discussion
3) Corneal Limbus: to irradiate or not, an update
16:00-16:05 Pro Majo, François (Switzerland) invited
16:05-16:10 Contra Tba 16:10-16:20 Discussion
4) PRK and CXL – in parallel or sequentially
16.20-16.30 Incidence of Emmetropia in Keratoconus cases Treated with same-session Corneal Collagen Cross-linking and Topography-guided PRK (A-54)
Al-Tuwairqi, Waleed (Saudi Arabia)
16:30-16.40 Limited topography guided surface ablation combined with corneal crosslinking for progressive keratokconus: a randomized trial. (A-34)
Schmidinger, Gerald (Austria) 16:40-16:55 Discussion
5) Transpepithelial
16:55-17:05 EPI-ON cross-linking: 3 years results and suggestions for the selection of the patient (A-10)
Gualdi, Luca (Italy)
17:05-17:15 Contra Hafezi, Farhard (Switzerland) 17:15-17:30 Discussion
17:30 The Theo Seiler Young Researcher Award
(Euro 500.00)
Hafezi, Farhard Mrochen, Michael Randleman, J. Bradley 17:45 Final remarks Hafezi, Farhad