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An RNA replication center assay for high content image based quantifications of human rhinovirus and coxsackievirus infections

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Figure

Figure 1 MabJ2 detects viral replication-induced dsRNA in high content image based assays
Figure 2 ICAM-1 receptor blocking antibodies abolish the formation of dsRNA replication centers by major group HRVs and CVA21HeLa cells were pre-incubated with anti-ICAM-1 mab15.2L for 30 min and infected with indicated HRV and CV serotypes
Figure 3 Appearance of dsRNA replication centers is time, dose and temperature dependent and correlates with emergence ofinfectious titres
Figure 4 Formation of dsRNA replication centers can be inhibited by pleconaril or guanidine-HCl
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