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Inhibition of poly(ADP-ribose) polymerase 1 protects against acute myeloid leukemia by suppressing the myeloproliferative leukemia virus oncogene

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Academic year: 2020

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Figure 1: Aberrant expression of poly(ADP-ribose) polymerase 1 (PARP-1) in acute myeloid leukemia (AML) patients and effect of PARP-1 inhibition on proliferation and cell cycle in AML cell lines
Figure 2: Effect of PARP-1 inhibition on apoptosis and molecular pathways in AML cell lines
Figure 3: PARP-1 inhibition improves AML prognosis in vivo in AML mice. A. Fluorescent microscopy and flow cytometry of C1498 cells transduced by a lentivirus with a GFP reporter
Table 1: Results of microarray analysis of the genes with over 2-fold upregulation following PARP-1 inhibition
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