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Use of Shotgun Metagenome Sequencing To Detect Fecal Colonization with Multidrug Resistant Bacteria in Children

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TABLE 1 Qualitative fecal screening cultures for detection of MDRbacteria in high-risk inpatients requires additional labor-intensiveevaluation to minimize false-positive results
FIG 2 Box and whisker plot of microbiome diversity (a) and resistome diversity (b) by Shannon Index using the median and interquartile ranges for each cohort.
FIG 3 Bubble graphs showing relative changes in the relative abundances of all species in the microbiome (a) and all antibiotic resistance genes in the resistome(b) after classification into clinically relevant categories between cohorts
TABLE 3 Detection of fecal colonization by culture and shotgun meta-genome sequencing in high-risk inpatients had only fair agreementbetween these two methodologiesa
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