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Inducible mouse models illuminate parameters influencing epigenetic inheritance

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Figure

Fig. 1. Phenotypic analysis of prenatally exposed CMV-GFP transgenic mice.  assay for GFP induction
Fig. 2. Epigenetic lesions at the CMV promoter in adult tissues.(A,B) Epigenetic lesions in lymphocytes
Fig. 3. Effects of rtTA on the CMV-GFP transgene in ES cells. Cellsdays of Dox exposure
Fig. 4. Fetal Dox exposure silences a randomly integrated CMVpromoter in the ensuing adults, but the effect is non-heritable.transgene (top) and a co-integrated transgene (bottom), the formerdiffering from the CMV-GFP transgene (Fig
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