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Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system

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Figure

Fig. 1. Xenopusconditioned medium from HEK 293T cells labelled with mouse (M), chick (C) and zebrafish (Z) RDH10 proteins
Fig. 2. Expression of Xenopus
Fig. 3. Retinoic acid downregulates XRDH10 and treated from stage 11 onwards with 0.05% ethanol as a control (E) or 5inhibitors disulfiram (10(A,B,E-L) and tailbud (C,D) stage
Fig. 4. XRDH10 induces retinoic acid signalling and differentiallyaffects organizer gene expression.XCYP26A1normal head and tail development
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