A genome wide association study of copy number variation identifies putative loci associated with osteoarthritis in Koreans

We performed a meta-analysis of 9 GWAS that included patients with knee or hip OA and control subjects of European descent: the deCODE study from Ice- land (20), 3 collections from

Most of the previously reported T2D-associated loci from earlier GWAS showed consistency in direction of association with similar effect sizes in Indo-European subjects of the

independent locus was taken for replication in three studies (n =4,011): Leiden hand OA studies (Genetics osteoARthritis and progression (GARP) study & the Leiden Longevity

6 A recent glioma genome-wide association study (GWAS) meta-analysis validated 12 previously reported.. risk loci, and identified 13 new

Conclusion Our study replicates the association, previously reported in European Caucasians, of TXNDC3 with knee OA susceptibility in an East Asian

Table 2: Association results for new independent secondary variants identified at (a) novel loci and (b) previously reported blood pressure 723. loci from either UK Biobank-GWAS

Keywords: PARK2 , Autism spectrum disorder (ASD), Copy number variations (CNVs), Family study, Gene

11 Furthermore, the linkage signal for Digit Span on chromosome 2p25.2 overlaps with the suggestive signal on 2p34.5 that was reported previously in the ASP study 11 and also with