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Dynamic transcriptional symmetry breaking in pre implantation mammalian embryo development revealed by single cell RNA seq

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Figure

Fig. 1. Expression biases in two-cellblastomeres approximately follow a binomialdistribution pattern
Fig. 2. Zygotic transcriptional activation elevates initial blastomere-to-blastomere biases
Fig. 3. Multiplied partitioning errors and elevated overall blastomere-to-blastomere biases during the two- to 16-cell stages
Fig. 4. Trends of transcriptional asymmetry during the two- to 16-cell embryo stages reveals monostable and bistable patterns
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