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Genome wide view of TGFβ/Foxh1 regulation of the early mesendoderm program

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Figure

Fig. 1. Foxh1 is crucial for mesendoderm formation. (A) Distribution ofmarkers(F) Early gastrula cleared lysates were immunoprecipitated using either pananti-Smad2 or anti-Smad1 polyclonal antibodies covalently coupled to beads.Bound proteins were subjecte
Table S1). Fig. 2A-D show read-mapping densities (tracks 3-6 in
Fig. 3. Motif analyses of Foxh1 and Smad2/3 peaks.Foxh1-bound (A) and Smad2/3-bound (B) regions (151 bpnovomatched manually (see citations incentered on peak summits) were retrieved to perform de motif analysis
Fig. 4. Functional relationships between Foxh1and Smad2/3 binding, and differential genecontrols
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