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AMERICAN

ACADEMY

OF

PEDIATRICS

COMMITTEE ON ENVIRONMENTAL HAZARDS

LEAD

CONTENT

OF

PAINT

APPLIED

TO

SURFACES

ACCESSIBLE

TO

YOUNG

CHILDREN

918

PEDIATRICS, Vol, 49, No. 6, June 1972

12. Kaufman, N. A., Kapitulnik, M. S., and

Blond-helm, S. H. : The adsorption of bilirubin by Sephadex and its relationship to the criteria for exchange transfusion. PEDIATRICS, 44:

543, 1969.

13. Chan, C., Schiff, D., and Stem, L.:

Competi-live binding of free fatty acids and bilirubin

to albumin. Differences in HBABA dye vs.

Sephadex G-25, interpretation of results. Clin. Biochem., 4:208, 1971.

T

HE Committee on Environmental

Haz-ards has recommended that the Amen-can National Standards Institute (ANSI)

revise that portion of the American

Stan-dard Z66.1/64 pertaining to the lead con-tent of paint downward from the present

1% to “minimum traces” or <0.06% of the

total weight of the contained solid,

includ-ing pigment, film solids, and driers. This

recommendation is based on a study of

re-cently published materia1s’ which

ap-peared after the 1% voluntary standard for lead was originally established in 1955 by ANSI.

At the same time, in response to the no-tice in the Federal Register of November 2,

1971 (21 CFR Part 191

),

the Committee recommended that Federal standards for lead content of paint used on surfaces

ac-0 This DPI is concerned primarily with mere-ments in oral intake of inorganic lead salts. In calculating this DPI, it was assumed that average daily respiratory exposure in most urban areas is approximately 2 tg Pb/rn’. Any significant

in-crease in respiratory intake would have to be given added weight because respiratory retention is

esti-mated at 35 to 40% of very small lead-bearing

par-ticulates in the lower respiratory tract. Assimila-tion in the gastrointestinal tract is estimated at

5 to 10% of oral intake. It is understood that the

comments in this statement apply almost exclu-sively to increments in oral intake in the presence

of constant but low levels of respiratory exposure (2 g Pb/rn’ on the average).

14. Schiff, D., Uian, G., and Stern, L.: Fixed drug

combinations and the displacement of biliru-bin from albumin. PEDIATRICS, 48:139, 1971.

Contributions to “Pharmacology for the Pedi-a:trician” and comments should be addressed to Dr. Charles F. Weiss, Department of Pediatrics, Urdvei*y Hospital, Box 739, Gainesville, Florida 32601.

cessible to young children be reduced to “minimum traces” on <0.06%, and that paints containing more than this amount of lead be banned as hazardous substances.

On review and evaluation of available data in children and adults, an ad hoc

corn-mittee (B. C. King, Chairman)’ recently

concluded that, for children, the maximum daily permissible intake

(

DPI

)

of lead from all sources should not exceed 300 tg Pb/day.#{176} If average daily intake is main-tamed below this level, blood lead concen-trations are unlikely to exceed 40 pg Pb/ 100 gm whole blood. At this level of in-take, it is estimated that the amount

as-siinilated by 1- to 3-year-old children could probably be excreted so no net increment in total body lead burden would be antici-pated. It is estimated that approximately one half of this 300 g Pb/day intake would be derived from usual food, water, and air, so intake from all other sources, on the

average, should not exceed 150 &g Pb/day. In particular, average daily intakes below this DPI would not be associated with any significant increment in soft tissue lead con-tent. It is this portion of the total body lead burden which appears to be responsi-ble for the known toxic effects of lead.

Available data indicate that increments

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AMERICAN ACADEMY OF PEDIATRICS 919

paint.

40 ‘.g Pb/100 gm whole blood. Such mere-ments may be associated with increases in the soft tissue component of the total body lead burden. At blood lead concentrations of 40 to 50 Pb/100 gm whole blood, some individuals may show minimal ad-verse metabolic response in the form of in-creased delta-aminolevulinic acid (ALA) excretion in urine.2 Increased ALA exere-tion in urine is the metabolic response most specffically associated with rising concen-trations of lead in the soft tissues. Incre-ments in total assimilation of lead to levels fivefold to tenfold above that assimilated from usual dietary intake, if continued for several weeks or months, clearly can bring such persons into the range of adverse metabolic effects and can be statistically correlated with blood lead levels in the range of 60 to 80 g Pb/100 gm whole blood. In some instances, persons with blood lead concentrations in this range may show

non-specific symptoms compatible with, but not diagnostic of, clinical plumbism. At blood lead concentrations of 60 tg Pb/100 gm whole blood or higher, x-ray evidence of abnormal skeletal mineralization at the

ends of growing long bones occurs in some

children when excessive intake persists for several weeks or months or longer. Such undesirable effects should be avoided in young, growing children.

To preserve health, prevent adverse metabolic effects attributable to increased soft tissue lead content in growing children, and minimize the risk of serious poisoning, the total daily intake of lead should be limited to < 300 Pb/day. A policy

state-ment recently approved by the Surgeon

General of the U. S. Public Health Service similarly concluded that blood lead

con-centrations > 40 pg Pb/100 gm whole

blood be considered indicative of undue exposure to lead and that children with blood lead concentrations in the 50 to 80 lJ.g Pb/100 gm whole blood range be con-sidered as possible cases of lead intoxica-lion and that such children require further medical evaluation.4 In view of the

preva-lence of pica in 1- to 3-year-old children, the permissible content of lead in paint

should be considered with the foregoing in

mind.

The content of lead in paint calculated as elemental lead and expressed as a per-cent of the total weight of the paint may be a good criterion by industry for the con-tent of lead in paint per Se. However, this is not a good criterion for evaluating the health hazard present in chips of paint from surface coverings of the walls, windows, doors, furniture, and other objects to which children may be exposed. It is the weight of lead in the chips that determines the health hazard. Recent studies5 indicate that the weight of multilayer paint chips can be related to the number of layers of paint applied to a surface. In this way, the amount of lead in single and multiple lay-ers of paint can be calculated from the per-centage of lead contained in the paint. Such

calculations are shown in Table I. For

ex-TABLE I

AMOUNT OF LEAD IN SINGLE AND MULTIPLE LAYERS

OF PAINT Vmisus PERCENT LEAD CONTENT IN PAINT

Painted Surface Coverings

Cul Lead Content of Paint Chip

of Exposed Surface (pg Pb)

Number of

Layers

Rounded Average Weigh1 of Paint

Chip (tag)

Lead Content in Paint, 1 .0% by Weight

I 6.5 65

6 40.0 400

10 65.0 650

Lead Content in Paint, 0.1% by Weight

1 6.5 6.5

6 40.0 40.0

10 65.0 65.0

Lead Content in Paint, 0.05% by Weight

1 6.5 3.

6 40.0 0.0

10 65.0 S.0

(3)

ample, studies at the U. S. Public Health Service Injury Control Laboratory, Provi-dence, Rhode Island, indicate that 1 sq cm of one layer of interior paint may weigh

5.2 to 8.0 mg

(

average, 6.5 mg) and that

six layers of paint may weigh 37.0 to 40.6

mg

(

average, 38.8 ). Sixty-nine samples of multilayer paint chips obtained from old dwellings in Philadelphia were found to weigh 89 ± 33 mg per square centimeter

of exposed surface.

(

The term “square cen-timeter of exposed surface” is used here because of the difficulty in sampling a pre-cise and reproducible volume of paint under field conditions.

)

Forty milligrams of interior paint (six layers

)

containing 1% of lead in the final dried solids would con-tam 400 lL Pb. Using the same calculation,

a 10-layered paint surface containing 1% lead might contain 650 tg Pb/sq cm of ex-posed surface. The calculated dose in either instance is in excess of the calculated DPI

(

daily permissible intake ). One square centimeter of six layers of paint on a sur-face containing 0.1% lead would contain 40 ig Pb; whereas, at 0.05% lead, 1 sq cm of a six-layered surface would contain 20

lL Pb. In this last instance, ingestion of a

paint chip with 1 sq cm (6.25 cm2) of

ex-posed surface per day on the average can be calculated to provide a dose of 125 tg Pb. Thus, 125 Lg of lead from paint,

to-gether with an allowance of 150 &g of lead from the usual lead content of food, water, and air approaches the DPI of 300 g Pb from all sources but would make little al-lowance for other nondietary sources the child may encounter.2’6

Also to be considered is the prevalence of pica in young children. It is estimated that approximately 50% of children between 1 and 3 years of age repetitively ingest non-food substances. Abdominal x-rays obtained

in the diagnostic evaluation of children sus-pected of having lead poisoning indicate

that large quantities of foreign substances

(

such as paint, putty, and plaster) may be ingested, often without the parents’ aware-ness.

Not only should the present ANSI

stan-dard be reduced to <0A%, but a similar Federal standard for lead is also needed to minimize lead as a health hazard to future generations of children. At the present time, lead poisoning as seen in children is related to old, deteriorated housing, so a Federal standard is unlikely to have a significant impact on plumbism as now seen. However, as this old housing is replaced or rehabili-tated, safe surface covering should be used

to minimize hazards to the health of future

children. Because pica has been a well-rec-ognized habit among humans for many cen-turies, it appears unlikely that this behav-ioral pattern will quickly change.

The American Academy of Pediatrics therefore endorses the principle contained

in the petition filed with the Commissioner of the Food and Drug Administration that paints containing more than minute traces of lead be declared as banned, hazardous substances. It appears that cautionary la-beling will not adequately protect the

pub-lic’s health and safety.

It should also be noted that therapy is not effective in reversing or preventing per-manent brain damage associated with Se-vere forms of acute lead poisoning such as acute encephalopathy. It is currently esti-mated that 40% or more of survivors of en-cephalopathy sustain permanent brain damage. To provide a margin of safety

(4)

AMERICAN ACADEMY OF PEDIATRICS 921

factor appears to be a minimum

require-ment.

ADDENDUM

On March 10, 1972, regulations were published

by the Food and Drug Administration which would ban as hazardous substances the shipment in inter-state commerce of paints and similar surface coat-ing materials which contain more than 0.06% levels

of lead. The regulation will become effective

De-cember 31, 1973. As an interim measure, the regu-lation bans as hazardous substances the shipment

in interstate commerce of all paints containing

more than 0.5% levels of lead beginning

Decem-ber 31, 1972.

The regulation also will apply to paint or similar surface coating materials of articles intended for use by children, including toys.

COMMITTEE ON ENVIRONMENTAL

HAZARDS

PAUL F. WEHRLE, M.D., Chairman

ROBERT L. Biu’r, M.D.

J.

JULIAN CHISOLM, JR., M.D.

JOHN L. Doyu, M.D.

EMMErr L. FACAN, M.D. LAURENCE FINBERC, M.D.

ROBERT W. Miua, M.D.

ANDR#{201}

J.

NAHMIAS, M.D.

G. D. CARLYLE THOMPSON, M.D.

ROBERT

J.

M. HORTON, M.D., Const,ltant

REFERENCES

1. King, B. C. : Maximum daily intake of lead without excessive body lead-burden in

chil-dren. Amer. J. Dis. Child, 122:337, 1971.

2. Airborne Lead in Perspective, report of Corn-mittee on Biologic Effects of Atmospheric

Pollutants of the Division of Medical Sci-ences, to be published by the National Re-search Council, National Academy of Sci-ences, Washington, D.C., 1971.

3. Chisoim,

J. J.,

Jr. : Increased lead absorption: Toxicological considerations. PEDIAmIc5, 48: 349, 1971.

4. Medical aspects of childhood lead poisoning:

Statement approved by surgeon general, U.S.P.H.S. PEDIATRICS, 48:464, 1971.

5. King, B. C. : Personal communication.

6. Hunt, W. F., Jr., Pinkerton, C., McNulty, 0.,

and Creason, J. P. : The 77 mid-western city study: A study of trace element pollution of the air. Presented at Fourth Annual

Confer-ence on Trace Substances, University of

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1972;49;918

Pediatrics

Nahmias, G. D. Carlyle Thompson and Robert J. M. Horton

Jr., John L. Doyle, Emmett L. Fagan, Laurence Finberg, Robert W. Miller, André J.

Committee on Environmental Hazards, Paul F. Wehrle, Robert L. Brent, J. Julian Chisolm,

APPLIED TO SURFACES ACCESSIBLE TO YOUNG CHILDREN

COMMITTEE ON ENVIRONMENTAL HAZARDS: LEAD CONTENT OF PAINT

Services

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including high resolution figures, can be found at:

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entirety can be found online at:

Information about reproducing this article in parts (figures, tables) or in its

Reprints

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(6)

1972;49;918

Pediatrics

Nahmias, G. D. Carlyle Thompson and Robert J. M. Horton

Jr., John L. Doyle, Emmett L. Fagan, Laurence Finberg, Robert W. Miller, André J.

Committee on Environmental Hazards, Paul F. Wehrle, Robert L. Brent, J. Julian Chisolm,

APPLIED TO SURFACES ACCESSIBLE TO YOUNG CHILDREN

COMMITTEE ON ENVIRONMENTAL HAZARDS: LEAD CONTENT OF PAINT

http://pediatrics.aappublications.org/content/49/6/918

the World Wide Web at:

The online version of this article, along with updated information and services, is located on

American Academy of Pediatrics. All rights reserved. Print ISSN: 1073-0397.

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