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Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis

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Figure

Fig. 1 mRNA expression of modulated proteins in CFPAC-1 shENO1cells. Using real-time PCR, mRNA expression of different proteins wasinvestigated in CFPAC-1 shENO1 cells
Fig. 2 Morphological analysis and roughness measurements of shENO1 cells.actin (Phalloidin-TRITC,level of nuclei
Fig. 3 Adhesion ability of ENO1-silenced PDA cells. Adhesive potential of shENO1 and control CFPAC-1 cells was evaluated by culturing cells for1 h on fibronectin (a), collagen I (b), collagen IV (c), and vitronectin (d)
Fig. 5 Analysis of uPAR/integrins pathways. Western blot analysis on total lysates of shENO1 and shCTRL CFPAC-1 cells was carried out to investigatelevels of (a) phospho- and total ERK1-2, (b) activated and total RAC, (c) phospho- and total Src, (d) phosph
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