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ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function

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Figure

Figure 1: ERβ1 regulates mutant p53 target genes. (A–C) TNBC cells were stably infected with lentivirus containing an empty vector (Lenti) or pLenti-FLAG-ERβ1 plasmid (ERβ1)
Figure 2: ERβ1 decreases cell invasion by regulating mutant p53 target genes. (A–B) H1299 cells after stable transfection with empty vectors (control), or recombinant mutant p53143A or p53143A and ERβ1 plasmids (A) as well as mutant p53175H or p53175H and
Figure 3: ERβ1 interacts with mutant p53 and p63. (A) Lysates from control and ERβ1-expressing MDA-MB-231 cells (left) or control, p53143A-, and p53143A/ERβ1-expressing H1299 cells (middle) were immunoprecipitated with anti-p53 antibody, followed by immuno
Figure 4: p63 affects the regulation of mutant p53 by ERβ1. (A) mRNA levels of the p63 target genes K14 and BCL-2 in control and ERβ1-expressing MDA-MB-231 cells
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