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Original Article LOXL1 regulates cell apoptosis and migration in human neuroglioma U87 and U251 cells via Wnt/β-catenin signaling

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Academic year: 2020

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Figure

Table 1. Sequence of primers and shRNAs
Figure 2. Knockdown LOXL1 inhibits GLIOMA cell proliferation and growth. (A) Expression of LOXL1 is significantly down-regulated in indicated cell lines after stably silencing LOXL1.Silencing LOXL1 inhibits U87MG (A) and U251 (B) cell viability
Figure 3. Ectopic expression of LOXL1 promotes NHA cell proliferation and growth. A: Expression of LOXL1 is significantly elevated in NHA cell when ec-topic expressed LOXL1 in NHA cell lines
Figure 4. LOXL1 regulates Wnt/β-catenin signaling in glioma cell lines. (A, B) Dual luciferase reporter assays re-vealed that depletion of LOXL1 significantly inhibits Wnt/β-catenin signaling in U87MG (A) and U251 (B) cells

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