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Adalimumab discontinuation in patients with early rheumatoid arthritis who were initially treated with methotrexate alone or in combination with adalimumab: 1 year outcomes of the HOPEFUL 2 study

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Academic year: 2020

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Figure

Figure 1Study designs of HOPEFUL-1 and HOPEFUL-2. The HOPEFUL-1 study comprised a 26-week randomised phase(ADA + MTX (intensive therapy) vs MTX alone (standard therapy)) followed by a 26-week open-label phase (all patients receivedADA + MTX)
Figure 2Patient dispositions throughout HOPEFUL-1 and HOPEFUL-2. ADA, adalimumab.
Table 1Patients’ baseline characteristics at weeks 0 and 52
Table 2Clinical, functional and structural outcomes of patients including those who failed to achieve stable LDA at week 52
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