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Prothrombin complex concentrates and a specific antidote to dabigatran are effective ex vivo in reversing the effects of dabigatran in an anticoagulation/liver trauma experimental model

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Academic year: 2020

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Figure

Table 1 Plasma concentration (activity, measured by diluted thrombin time) of dabigatran (ng/mL) during the study
Figure 2 aPTT at the low dabigatran (A), high dabigatran (B)and post-trauma (C) time-points
Figure 3 Thromboelastometry parameters after oralconcentrate; aPCC, activated PCC; rFVIIa, recombinant activatedadministration of dabigatran etexilate
Table 2 Haematological parameters and fibrinogen concentration during the study
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