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Dichloroacetic acid-induced testicular toxicity in male rats and the protective effect of date fruit extract

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Fig. 1 Effect of ADE on reproductive organs weights ((a) testis and (b) epididymis) in male rats treated with two different doses of DCA (0.5 and 2g/l).Different letters (a-d) indicate significant differences between groups at p<0.05 by Duncan’s test
Table 1 Effect of ADE on plasma levels of FSH, LH and testosteronein male rats treated with two different doses of DCA
Fig. 2 Testis section of control and ADE treated groups showing (a) normal histological architecture pattern of seminiferous tubules with (b)normal germ cells (#) and interstitial connective tissue (*) (H&E, (a) 100× and (b) 400×)
Fig. 5 Testis sections of rats treated with (a) ADE and DCA at 0.5g/l showing significant improvement of histological architecture with normalseminiferous and sertoli cells, and (b) those treated with ADE and DCA at 2g/l showing mild degenerative changes of seminiferous tubules, mildcongestion and edema (H&E, 100×)

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