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Development of Transdermal Delivery System of Dexamethasone, Palonosetron and Aprepitant for Combination Antiemetic Therapy

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Academic year: 2020

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Figure

Table 1: Physicochemical and biopharmaceutics related properties of dexamethasone, palonosetron  hydrochloride and aprepitant.30
Table 2: Ex vivo permeation parameters observed in various treatments
Figure 1: Structure of (a) palonosetron hydrochloride (b) aprepitant and (c) dexamethasone.
Figure 6: Effect of various chemical skin permeation enhancers on the transdermal delivery of dexamethasone at 1.5% (w/w)

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