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Dimerization of MORC2 through its C-terminal coiled-coil domain enhances chromatin dynamics and promotes DNA repair

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Figure

Fig. 1 MORC2 attenuates histone and DNA interaction.cells and subjected to salt solubilization assays
Fig. 2 MORC2 is required for altered nucleosome stability after DNA damage.CPT for 1 h
Fig. 3 MORC2 promotes the recruitment of DNA repair proteins to DNA damage sites and cell survival in response to DNA damage.MORC2 KO HeLa (antibodies
Fig. 5 The C-terminal coiled-coil domain of MORC2 is required for its dimer formation.MORC2, HA-MORC2lysates were subjected to cross-linking assay, followed by immunoblotting with an anti-Flag antibody.were counterstained with DAPI
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