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The CXCR4 antagonist plerixafor (AMD3100) promotes proliferation of Ewing sarcoma cell lines in vitro and activates receptor tyrosine kinase signaling

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Figure

Fig. 1 Plerixafor (AMD3100) but not CXCL12 promotes proliferation of Ewing sarcoma cell lines in vitro
Fig. 2 Ewing sarcoma cell lines show chemotactic migration to(0.1grown in standard conditions, documented by bright field microscopyat 40× magnification
Fig. 3 Ewing sarcoma cell lines group into CXCR4-high and -low surface expression.isoforms
Fig. 4 Plerixafor-induced proliferation does not require substantial CXCR4 surface expression but is associated with AKT activation
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