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Cancer detection and biopsy classification using concurrent histopathological and metabolomic analysis of core biopsies

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Figure

Figure 1 Schematic outline of method workflow. Flow diagram of the intact biopsy extraction protocol and tissue grinding protocol for atissue biopsy and a 30 mg tissue piece
Figure 2 Number and identity of metabolites obtained with intact biopsy method and the standard ground tissue extraction methodThe total number of metabolites detected using each sampling and extraction protocol (30 mg tissue, intact biopsy, ground biopsy)
Figure 4 Histology of prostate biopsy samples. Human prostate biopsy samples were processed using the intact biopsy method in 80%methanol followed by paraffin embedding and sectioning
Table 1 Number of metabolites detected followingvarious incubation times
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