• No results found

Original Article Blocking follistatin-like 1 attenuates liver fibrosis in mice by regulating transforming growth factor-beta signaling

N/A
N/A
Info
Download
Protected

Academic year: 2020

Share "Original Article Blocking follistatin-like 1 attenuates liver fibrosis in mice by regulating transforming growth factor-beta signaling"

Copied!
11
0
0

Loading.... (view fulltext now)

Download now ( 11 Page )

Full text

Loading

Figure

Figure 1. (A) IHC images of FSTL1 expression in human cirrhotic liver tissues (a) and normal liver tissues (b)
Figure 2. Primary HSCs isolated from mice were fixed at five days. ICC images showed that the activation of HSCs treated with IgG was faster than that of HSCs treated with FSTL1.
Figure 3. (A) Treatment of HSCs with an FSTL1 mAb had no significant effect on cell proliferation in vitro; (B) Transwell assay showed that HSC-T6 cells treated with the FSTL1 mAb (c, d) exhibited reduced migration compared with cells treated with IgG (a, b) in vitro.
Figure 4. (A) Sirius Red staining showed that CCl4-induced mice treated with an FSTL1 mAb (c, d) exhibited reduced collagen accumulation, and attenu-ation of liver fibrosis compared with CCl4-induced mice treated with IgG (a, b) in vivo; (B) Masson staining showed that treatment of CCl4-induced mice with the FSTL1 mAb (b) resulted in attenuation of liver fibrosis in vivo; (C) The ALT and AST detection results showed that treatment of mice with the FSTL1 mAb resulted in attenuation of liver injury caused by CCl4.
+4

References

Download now ( PDF - 11 Page - 2.23 MB )

Related documents

In silico Molecular Docking and Molecular Dynamics Applications in the Designing of a New Mosquito Repellent from the Plant Calotropis gigantea Targeting the Odorant Binding Protein of Culex quinquefasciatus

In the present investigation, biological activity prediction, molecular docking and molecular dynamics (MD) simulation experiments were performed on potential ligands of

Trends in beliefs about the harmfulness and use of stop-smoking medications and smokeless tobacco products among cigarettes smokers: Findings from the ITC four-country survey

This study explores changing trends in the beliefs about the harmfulness and use of stop smoking medications and smokeless tobacco in adult smokers in four countries where

Improving trauma care in India: a recommendation for the implementation of ATLS training for emergency department medical officers

We also examined whether previous completion of an ATLS (or equivalent) course, or self-rated years of training in the management of trauma patients ( ‘ trauma training ’ ) impact-

Icp-Ms Analysis of Lanthanide-Doped Nanoparticles: A Quantitative and Multiplexing Approach to Investigate Biodistribution, Blood Clearance, and Targeting

Zeta potential (surface charge) titration of native GC-SPIO, glycidol GC-SPIO and dextran SPIO nanoparticles at 100 µ g/mL nanoparticle concentration in 10 mM HEPES buffer at

Aim-Oriented Empiricism and the Metaphysics of Science

associated methods as it improves its knowledge: there is something like positive feedback between them (which helps account for the explosive growth in scientific knowledge).

The Pathogenesis of Duodenal Ulcer and the Role of Helicobacter pylori in This Disease: A Systematic Review

The late phase of duodenal ulcer is a corrosive process caused by local aggressive factors, including gastric acid and pepsin, H.. pylori, mechanical abrasion, and chemical erosion

A TRADITIONAL ART PRACTICE IN THE SATRIYA CULTURE OF ASSAM: A SPECIAL REFERENCE OF THE PAINTINGS OF BHAGAVATA-PURANA, X (ADI-DASAMA)

Author Naren Kalita opined that “It is a fact that the painting of the Chitra Bhagavata represents an advance stage of development at the Satriya painting style encountered in