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Imaging Brain Oxygenation with MRI Using Blood Oxygenation Approaches: Methods, Validation, and Clinical Applications

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Figure

FIG 1. Aof 60%.adapted from Christen et al.field B0., 3D representation of a microvascular network acquired with 2-photon microscopy and orientation of the MR imaging main magnetic B, Simulation of the magnetic field distribution in 1 section of the voxel re
FIG 2. Results from a multiparametric qBOLD approach. A, MR imaging estimates of SO2 as a function of directly measured SvO2 of the sagittalsinus in rats
FIG 3. Parametric maps obtained with a quantitative BOLD approach by using a multiecho gradient-echo and spin-echo echo-planar imagingarrowAdapted from Christen et al.method in a healthy subject (A) and a patient with stroke (B)
FIG 4. Oxygen-sensitive MR imaging in the setting of cerebrovascular challenge during a 2-minute inhalation of carbogen gas (95% O, 5% CO).Images were acquired by using a multiple spin- and gradient-echo pulse sequence that enables the measurement of T2* a
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