Program Application for CME credits submitted

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Falk Workshop

Workshop on Oral cGVHD &

Clinical Practice in cGVHD

November 22 – 23, 2013

University Hospital Regensburg

Regensburg, Germany

Program

Application for

CME credits

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Preface . . . 4

Scientiﬁc Program . . . 6

List of Speakers . . . 9

Information . . . 13

CME credits for the Falk Workshop have been applied for at the European Union of

Medical Specialists (UEMS).

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4

Preface

Dear Colleagues,

We are pleased to invite you to the Workshop on Oral cGVHD & Clinical Practice in cGVHD 2013 held in Regensburg. Chronic GVHD continues to be a challenge in clinical practice balancing GVHD treatment against toxicity and infectious morbidity. The workshop will focus on two aspects in clinical care of patients with chronic GVHD.

The workshop on oral GVHD will provide a comprehensive overview on pathophysiology, diagnosis, immunosuppressive and supportive treatment as well as long term complications of oral chronic GVHD.

The workshop on clinical practice of chronic GVHD will focus on daily routine and will be organized in case seminars in small groups each headed by a multidisciplinary team (Senior Transplant Physician, Pathologist, Dermatologist, Oral Surgeon, Physical Therapist, Ophthalmologist, Transplant Nurse). Additional specialties will be added if required. The aim is to evaluate patients with chronic GVHD including diagnosis, histopathology, severity grading, to discuss treatment options to develop a treatment plan including supportive care. Since different groups will evaluate and the same patients, this approach will permit the indentification of areas of consensus as well as fields with further need of clarification. In contrast to the last meetings where will be an upper limit for participants during the workshop on Saturday.

Both workshops are supported by Falk Foundation e.V.

M. Endinger, W. Herr, E. Holler, E. Huber, J. Meier, T.E. Reichert, D. Wolff (Regensburg) H. Greinix, A. Lawitschka (Vienna)

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Falk Workshop

Workshop on Oral cGVHD &

Clinical practice in cGVHD

University Hospital Regensburg

Regensburg, Germany

Registration:

Friday, November 22, 2013

7.00 – 19.00 h

at the congress ofﬁ ce

Scientiﬁ c Organization

Regensburg (Germany):

R. Andreesen, Regensburg

W. Herr, Regensburg

E. Holler, Regensburg

J. Meier, Regensburg

T. E. Reichert, Regensburg

D. Wolff, Regensburg

Congress Venue:

University Hospital Regensburg

Franz-Josef-Strauss-Allee 11

93053 Regensburg

Germany

Information:

Prof. Dr. Daniel Wolff

Dept. of Medicine III,

Hematology and Oncology

University Hospital Regensburg

Franz-Josef Strauss-Allee 11

93053 Regensburg

Germany

Tel:

+49 (0)941-944-5531

Fax:

+49 (0)941-944-5543

E-Mail: daniel.wolff@ukr.de

Ofﬁ cial Language:

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6

Friday, November 22, 2013

Workshop on Oral cGVHD

Introduction

(Großer Hörsaal)

Chair:

W. Herr, Regensburg; W. Wagner, Mainz

8.30 Introduction

E. Holler,

Regensburg

T. E. Reichert,

Regensburg

8.45 Pathophysiology of oral cGVHD

J. Meier,

Regensburg

9.15 Proteomics in oral cGVHD

J. W. Mays,

Bethesda

9.30 Histopathology of oral cGVHD

M. Imanguli,

Dallas

9.50 Clinical manifestations and diagnosis of oral cGVHD

S. Elad,

Rochester

10.15 Coffee

break

Immunosuppressive treatment of oral cGVHD

Chair:

F. Ayuk, Hamburg; S. Elad, Rochester

10.45 Topical steroids

S. Elad,

Rochester

11.10 Topical calcineurin-inhibitors

M. Albert,

Munich

11.25 Oral PUVA and UVB

N. S. Treister,

Boston

11.40 Systemic treatment

H. Greinix,

Vienna

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Friday, November 22, 2013

Supportive care of oral cGVHD

Chair:

R. G. Meyer, Mainz; N. S. Treister, Boston

12.45 Supportive care

E. M. Wagner,

Mainz

13.05 Laser treatment of oral cGVHD

J. Meier,

Regensburg

13.20 Paediatric aspects

A. Lawitschka,

Vienna

13.40 Treatment of oral sclerosis

N. S. Treister,

Boston

13.55 Dental issues in oral GVHD

S. Hahnel,

Regensburg

14.10 Secondary malignancies in oral GVHD

T. E. Reichert,

Regensburg

14.30 Conclusion

Chair:

S. Elad, Rochester; J. W. Mays, Bethesda; J. Meier, Regensburg;

T. E. Reichert, Regensburg; N.S. Treister, Boston; D. Wolff, Regensburg

12.00 – 15.00 Meeting of pathology groups

(Institute of Pathology)

Workshop on Clinical Practice cGVHD

Current concepts in clinical care of cGVHD

Chair:

J. Halter, Basel; S. Z. Pavletic , Bethesda

15.45 Pathophysiology of cGVHD

E. Holler,

Regensburg

16.15 Diagnosis of cGVHD

H. Greinix,

Vienna

16.45 Histopathology of cGVHD

E. Huber,

Regensburg

17.15 Coffee

break

17.30 Response evaluation of cGVHD

S. Lee,

Seattle

18.00 Treatment of cGVHD

D. Wolff,

Regensburg

18.30 Supportive care

I. Hilgendorf,

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Saturday, November 23, 2013

Workshop on clinical practice in cGVHD

8.30 Introduction and Instruction

(Großer Hörsaal)

Chair:

S. Lee, Seattle; D. Wolff, Regensburg

9.00 First part of the Workshop (3 patients per group)

12.00 Lunch

12.45 Second part of the Workshop (3 patients per group)

15.45 Coffee

break

16.00 Conclusions

GVHD teams are headed by:

H. Greinix, Vienna; S. Z. Pavletic, Bethesda; S. Lee, Seattle; J. Halter, Basel;

E. Holler, Regensburg; F. Ayuk, Hamburg

The GVHD teams are supported by:

Pathology:

H. A. Baba, Essen; E. Huber, Regensburg; A. Kreft, Mainz; F. Länger, Hannover;

T. Longerich, Heidelberg; A. Tzankow, Basel

Dermatology:

P. Häusermann, Basel; U. Hillen, Essen; U. Just, Vienna; C. Marks, Freiburg;

E. von Stebut-Borschitz, Mainz; M. Ziemer, Leipzig

Ophthalmology:

C. Blecha, Regensburg; T. Dietrich, Regensburg; P. Eberwein, Freiburg;

D. Goldblum, Basel; T. Meyer-ter-Vehn, Würzburg; A. Tomaszewski, Essen

Oral Medicine:

S. Elad, Rochester; M. Imanguli, Dallas; J. Meier, Regensburg; N. S. Treister, Boston;

W. Wagner, Mainz; T. Waltimo, Basel; J. W. Mays, Bethesda

Physiotherapy:

T. Daikeler, Basel; M. Ebnöther, Rheinfelden; C. Kalt, Basel; M. Kramer, Leipzig;

L. Kreher, Regensburg; S.-F. Meier, Regensburg; S. Meurer, Rheinfelden

Pulmology:

G. Hildebrandt, Salt Lake City; T. Lange, Regensburg; C. Schulz, Regensburg

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List of Speakers, Moderators and Scientiﬁc Organizers

PD Dr. Michael Albert

Abteilung für Pädiatrische Hämatologie und Onkologie

Dr. von Haunersches Kinderspital der LMU Lindwurmstr. 4

80337 München Germany

michael.albert@med.uni-muenchen.de

Prof. Dr. Reinhard Andreesen

Klinik für Innere Medizin III, Hämatologie und Onkologie Universitätsklinikum Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg Germany reinhard.andreesen@ukr.de PD Dr. Francis Ayuk Interdisziplinäre Klinik für Stammzelltransplantation Universitätsklinikum Hamburg-Eppendorf Martinistr. 52 20246 Hamburg Germany ayuketan@uke.de

Prof. Dr. Hideo A. Baba

Institut für Pathologie Universitätsklinikum Essen Hufelandstr. 55 45147 Essen Germany hideo.baba@uk-essen.de Dr. Christiane Blecha Klinik für Augenheilkunde Universitätsklinikum Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg Germany blecha@eye-regensburg.de PD Dr. Thomas Daikeler Rheumatologie Universitätsspital Basel Petersgraben 4 4031 Basel Switzerland thomas.daikeler@usb.ch PD Dr. Tina Dietrich Klinik für Augenheilkunde Universitätsklinikum Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg Germany dietrich@eye-regensburg.de Dr. Philipp Eberwein Universitäts-Augenklinik Freiburg Killianstr. 5 79106 Freiburg Germany philipp.eberwein@uniklinik-freiburg.de Michaela Ebnöther Reha Rheinfelden Salinenstr. 98 4310 Rheinfelden Switzerland m.ebnoether@reha-rhf.ch

Prof. Dr. Sharon Elad

University of Rochester Medical Center Eastman Institute for Oral Health Division of Oral Medicine 625 Elmwood Ave. Rochester, NY 14620 USA

selad@urmc.rochester.edu

Prof. Dr. David Goldblum

Augenklinik Universitätsspital Basel Petersgraben 4 4031 Basel Switzerland david.goldblum@usb.ch

Prof. Dr. Hildegard Greinix

Medizinische Universität Wien Klinik für Innere Medizin I Knochenmarkstransplantation Waehringer Gürtel 18-20 1090 Wien

Austria

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10 PD Dr. Peter Häusermann Dermatologie Universitätsspital Basel Petersgraben 4 4031 Basel Switzerland phaeusermann@uhbs.ch PD Dr. Sebastian Hahnel

Poliklinik für zahnärztliche Prothetik Universitätsklinikum Regensburg 93042 Regensburg Germany sebastian.hahnel@ukr.de Dr. Jörg Halter Innere Medizin Kantonsspital Basel Petersgraben 4 4031 Basel Switzerland jhalter@uhbs.ch

Prof. Dr. Wolfgang Herr

Klinik für Innere Medizin III, Hämatologie und Onkologie Universitätsklinikum Regensburg 93042 Regensburg Germany wolfgang.herr@ukr.de Gerhard Hildebrandt, M.D. Division of Hematology Hematologic Malignancies Huntsman Cancer Institute University of Utah

2000 Circle of Hope, RM 4261 Salt Lake City

UT 84112-5550 USA

gerhard.hildebrandt@hsc.utah.edu

Dr. Inken Hilgendorf

Hämatologie/Onkologie Klinikum der Universität Rostock Ernst-Heydemann-Str. 7 18057 Rostock Germany inken.hilgendorf@med.uni-rostock.de PD Dr. Uwe Hillen Dermatologie Universitätsklinikum Essen Hufelandstr. 55 45147 Essen Germany uwe.hillen@uk-essen.de

Prof. Dr. Ernst Holler

Klinik für Innere Medizin III, Hämatologie und Onkologie Universitätsklinikum Regensburg 93042 Regensburg Germany ernst.holler@ukr.de Dr. Elisabeth Huber Institut für Pathologie Universitätsklinikum Regensburg 93042 Regensburg Germany elisabeth1.huber@ukr.de Matin Imanguli, DDS, M.D. University of Texas

Southwestern Medical Center Department of Otolaryngology 323 Harry Hines Boulevard Dallas, TX 75390-9035 USA

matin.imanguli@phhs.org

Dr. Ulrike Just

Dermatologie

Medizinische Universität Wien Währinger Gürtel 18-20 1090 Wien Austria ulrike.just@meduniwien.ac.at Kristina Kalt-Kägi Physiotherapie Felix Platter-Spital Burgfelderstrasse 101 4012 Basel Switzerland stina_kaegi@hotmail.com Dr. Maxi Kramer Industriestrasse 9 04229 Leipzig Germany joerg_kramer@email.de

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Dr. Andreas Kreft Institut für Pathologie Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz Germany andreas.kreft@unimedizin-mainz.de Luisa Kreher Abteilung für Physiotherapie Universitätsklinikum Regensburg 93042 Regensburg Germany luisa.kreher@ukr.de Dr. Florian Länger Institut für Pathologie MHH Hannover OE 5510 Carl-Neuberg-Str. 1 30625 Hannover Germany laenger.ﬂorian@mh-hannover.de Dr. Tobias Lange

Klinik für Innere Medizin II Universitätsklinikum Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg Germany tobias.lange@ukr.de Dr. Anita Lawitschka SCT Outpatient Clinic St. Anna Kinderspital Kinderspitalgasse 6 1090 Wien Austria anita.lawitschka@stanna.at Stephanie Lee, M.D. Professor of Medicine Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N. P.O. Box 19024 Seattle, WA 89109 USA sjlee@fhcrc.org PD Dr. Thomas Longerich Institut für Pathologie Universitätsklinikum Heidelberg Im Neuenheimer Feld 224 69120 Heidelberg Germany thomas.longerich@med.uni-heidelberg.de Dr. Christiane Marks Innere Medizin I Medizinische Universitätsklinik Hugstetter Str. 55 79106 Freiburg Germany christiane.marks@uniklinik-freiburg.de Jacqueline W. Mays, DDS, Ph.D.

NIDCR Clinical Research Fellow National Institute of Health Bldg 10, Rm 1N-118, MSC 1191 10 Center Drive Bethesda, MD 20892 USA maysjw@nidcr.nih.gov Dr. Dr. Johannes Meier

Klinik und Poliklinik für MKG-Chirurgie Universitätsklinikum Regensburg 93042 Regensburg Germany johannes.meier@ukr.de Sebastian-Florian Meier Abteilung für Physiotherapie Universitätsklinikum Regensburg 93042 Regensburg Germany sebastian-ﬂorian.meier@ukr.de Sonja Meurer Reha Rheinfelden Salinenstr. 98 4310 Rheinfelden Switzerland s. meurer@reha-rhf.ch PD Dr. Ralf G. Meyer

Hämatologie und Onkologie III. Medizinische Klinik u. Poliklinik Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz Germany ralf.meyer@unimedizin-mainz.de

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12 Dr. Tobias Meyer-ter-Vehn Universitäts-Augenklinik Josef-Schneider-Str.11 97080 Würzburg Germany meyer_t3@augenklinik.uni-wuerzburg.de Steven Z. Pavletic, M.D. Professor of Medicine National Cancer Institute Building 10 - Hatﬁeld CRC Room 4-3130 10 Center Drive Bethesda, MD 20892 USA pavletis@mail.nih.gov

Prof. Dr. Dr. Torsten E. Reichert

Klinik und Poliklinik für MKG-Chirurgie Universitätsklinikum Regensburg 93042 Regensburg

Germany

torsten.reichert@ukr.de

PD Dr. Christian Schulz

Klinik für Innere Medizin II Universitätsklinikum Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg Germany

christian.schulz@ukr.de

Prof. Dr. Esther von Stebut-Borschitz

Dermatologie Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz Germany vonstebu@uni-mainz.de Nathaniel S. Treister, DMD, DMSc

Brigham and Women‘s Hospital Division of Oral Medicine and Detistry 1620 Tremont Str., Suite BC-3-028 Boston, MA 02120

USA

ntreister@partners.org

Prof. Dr. Alexandar Tzankov

Head Histopathology and Autopsy Institute of Pathology

University Hospital Basel Schoenbeinstrasse 40 4031 Basel Switzerland atzankov@uhbs.ch Dr. Eva M. Wagner Innere Medizin

Hämatologie und Onkologie III. Medizinische Klinik u. Poliklinik Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz Germany eva.wagner@unimedizin-mainz.de

Prof. Dr. Dr. Wilfried Wagner

Klinik und Poliklinik für MKG-Chirurgie Augustusplatz 2

55131 Mainz Germany

wilfried.wagner@unimedizin-mainz.de

Prof. Dr. odont. Tuomas Waltimo

Klinik für Präventivzahnmedizin und Orale Mikrobiologie Departement Zahnmedizin Universität Basel Hebelstrasse 3 4056 Basel Switzerland tuomas.waltimo@usb.ch

Prof. Dr. Daniel Wolff

Klinik für Innere Medizin III, Hämatologie und Onkologie Universitätsklinikum Regensburg 93042 Regensburg Germany daniel.wolff@ukr.de Dr. Mirjana Ziemer Klinik für Dermatologie, Venerologie und Allergologie Philipp-Rosenthal-Str. 23 04103 Leipzig

Germany

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General Information

Prior

to the opening of the Falk Workshop in Regensburg

Falk Foundation e.V.

Telephone: +49 (0)761/1514-0

Congress Division

Telefax:

+49 (0)761/1514-359

Leinenweberstr. 5

E-mail:

symposia@falkfoundation.de

79108 Freiburg (Germany)

General Information

During

the Falk Workshop

University Hospital Regensburg

Telephone: +49 (0)175/7795327

Franz-Josef-Strauss-Allee 11

93053 Regensburg

Germany

Opening Hours:

Friday, November 22, 2013

7.00 - 19.00 h

Saturday, November 23, 2013

8.00 - 16.30 h

Congress Fees

The participation at the Falk Workshops is free of charge. Please be aware that the

number of participants is limited.

Registration is mandatory.

Refreshments during the coffee breaks and lunch on November 22-23 and dinner on

November 22 and a copy of the abstract volume of the Falk Workshop are also free

of charge.

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14

Registration

Congress registrations must reach the Falk Foundation e.V. by

October 31, 2013 at

the latest.

After receipt of the registration form, each participant will be provided with

conﬁrmation of his registration. On presentation of this conﬁrmation at the congress

ofﬁce in Regensburg participants will receive the congress folder containing name

badges, admission tickets and the abstract volume.

All participants will receive a written conﬁrmation of attendance and CME credits at

the end of the meeting.

Admission to Scientiﬁc Events

For admission to scientiﬁc events your name badge should be clearly visible.

Hotel Accommodation

If you would like to do a hotel reservation, please contact:

Tourist-Information Altes Rathaus

Rathausplatz 4

93047 Regensburg

Germany

Telephone: +49

(0)941/507-4410

E-mail: tourismus@regensburg.de

www.tourismus.regensburg.de/tourismus/Home/3854

For further local information please contact:

S. Blüml or G. Geissler

Dept. of Medicine III, Hematology and Oncology

University Hospital Regensburg

Germany

Telephone: +49 (0) 941-944-5542 or -5501

E-mail: susannna.blueml@ukr.de

gertraud.geissler@ukr.de

Airport

International Franz-Josef-Strauß-Airport Munich

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Directions to University Hospital Regensburg

Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg

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General Information:

FALK FOUNDATION e.V.

Leinenweberstr. 5 79108 Freiburg Germany Congress Division Telephone: +49(0)761/1514-0 Telefax: +49(0)761/1514-359 E-mail: symposia@falkfoundation.de www.falkfoundation.de P W S R E G e 1 -4 /2 0 1 3 /3 2 .5 0 0 S tü

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Falk Workshop

Workshop on oral cGVHD &

on clinical practice in cGVHD

November 22 – 23, 2013

University Hospital Regensburg

Regensburg, Germany

Evening

Activities

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Dinner at “Leerer Beutel“

Bertoldstr. 9, 93047 Regensburg

Friday, November 22, 2013

20.00 Uhr

Dinner with drinks

Free of charge, registration mandatory

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General Information:

FALK FOUNDATION e.V.

Leinenweberstr. 5 79108 Freiburg Germany Telephone: +49(0)761/1514-0 Telefax: +49(0)761/1514-359 E-mail: symposia@falkfoundation.de www.falkfoundation.org

Falk Foundat

ion e

. V

.

Congr

ess Division

Leinenweberstr

. 5

79108 Fr

eiburg

Germany

Please print or legibly stamp your name and pr

ofessional addr

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REGISTRATION CARD

Falk Workshop

November 22 – 23, 2013

Regensburg (Germany)

Reg

istrat

ion Deadl

ine

: October 31, 2013

Falk W orkshop W

orkshop on Oral cGVHD &

Cl in ical pract ice in cGVHD November 22 – 23, 2013 Regensburg (Germany) R

I will attend the Falk W

orkshop on Oral cGVHD on November 22, 2013

R

Meeting of pathology groups on November 22, 2013 (Institut of Pathology

, 12.00 -15.00 h)

R

I will attend the Falk W

orkshop on clinical cGVHD on November 23, 2013

(l

im

ited number of part

ic

ipants)

R

Dinner at “Leerer Beutel”

Friday

, November 22, 2013, 20.00 h