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Organization and expression of the developmentally regulated H1(o) histone gene in vertebrates

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Figure

Fig. 2. Schematicrepresentationof potentialrecognitionsitesfor factorsbindingto theproximal800 bp of themouseH1° promoter.RARE:retinoicacid responsiveelement.Shadedareas representsequenceelemenrsof unknownfunctionwhereproteinbinding(approximatemolecularmass in kDaJ has beenobservedin vitro.Othersequencemotifs(TATA box, AP-2 bindingsite,H4 box, Hlbox,Oct-likeelemenr,GC-richelement}representregulatorysequenceelementswhichhave also beenobservedin otherpromoters.The UCE elementis a sequencewhichhas beenobservedin the murine.humanand amphibianH1° promoters.Numbersabovethe factorsindicatethe approximatedistance(in bpI upstreamof thetranscriptionstart point(+ 1).

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