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DEVELOPMENT OF ANALYTICAL METHOD FOR IDENTIFICATION OF SIBUTRAMINE HCL IN TRADITIONAL MEDICINE USING SOLID PHASE EXTRACTION – HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

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Figure

Table 1: Comparison of SPE sibutramine HCl with and without acidification
Fig. 2: Chromatogram of sibutramine hydrochloride with acid-base addition variation
Fig. 4: Solid phase extraction of sibutramine hydrochloride with various orthophosphoric acid concentration
Fig. 5: Solid phase extraction of sibutramine hydrochloride with orthophosphoric acid 3.0% solvent
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