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BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions

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Figure

Figure 1 The need for biological replicates. We show smoothed methylation profiles for three normal samples (blue) and matched cancers(red) from the Hansen data [1]
Figure 2 Quality control plots. (a) M-bias plot for the Hansen data, a WGBS experiment on cancer samples
Figure 3 The advantages of smoothingLister data. The pink line is obtained by applying BSmooth to a the full data
Figure 4 Evaluation of the differentialy methylated regions finderdifferentially expression (FDRbased on the association between gene expression and methylation changes in the Tung data

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