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A 4 trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation

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Figure

Figure 1 Effect of TFM-C on cytokine production frommacrophages treated with LPS/PMA in the absence (open squares)or presence (solid circles) of TFM-C
Figure 2 The effect of TFM-C on CIA(open triangles) or vehicle (open squares) every other day from 21days after immunization
Figure 3 The effect of TFM-C on CAIA. A. Clinical scores of CAIAin B6 mice treated with 10 μg/g TFM-C (closed circles), celecoxib(open triangles) or vehicle (open squares) every other day from twodays before CAIA induction
Figure 4 TFM-C inhibits the mast cell activation in CAIAcelecoxib or vehicle as described in Figure 2.P
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