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Ivano Amelio 1, Alexey A. Antonov1 , Maria Valeria Catani 2, Renato Massoud2 Francesca Bernassola 2, Richard A. Knight1 , Gerry Melino 1,2,3 , Alessandro Rufini 1,4

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Figure

Figure 1: TAp73 enhances glycolytic flux. Increased glycolytic flux as suggested by reduced intracellular glucose and concomitant increased lactate and acetyl-CoA
Figure 2: Increased amino acid uptake in TAp73 expressing cells. Increased intracellular contents of numerous amino acids after short-time induction of TAp73β, probably reflecting increased uptake from culture medium
Figure 3: TAp73 regulates biosynthesis of phospholipids. Expression of TAp73β induces biosynthesis of membrane lipids, including a substantial increase in phosphoethanolamine
Figure 4: Enhanced polyamines biosynthesis induced by TAp73. Polyamines show a significant increase after 8h of TAp73βinduction
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