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Targeting type I interferon–mediated activation restores immune function in chronic HIV infection

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Figure

Figure 1. Chronic HIV infection results in elevated expression of activation and exhaustion markers and exhaustion of viral-specific CD8 cells
Figure 2. IFN-I signaling is chronically elevated during HIV-1 infection.CD4% among T cells in PBMCs from BLT mice after HIV infection (per group)
Figure 4. IFNR blockade treatment reduces viral load, and combination of ART and IFNR blockade promotes faster viral suppression and reduces viral reservoir

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