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A colitogenic memory CD4+ T cell population mediates gastrointestinal graft versus host disease

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Figure

Figure 1. CD4+and a 1:1 mixture of CD4nwith B6 spleen cells. Animals transplanted with spleen cells were treated with an isotype control (black squares, squares, transplanted with B6 Rag-1 BM alone (circles, (black squares, from B6.PL IL-23R+ T cells drive
Figure 2. CD11b and CD11c expression marks a CD4+cin–negative (7-AADIL-23R expression on colonic CD4days after transplantation
Figure 3. βexpressed the IL-23R. (normal B6 mouse. (these 2 that lacked expression of either 2 Integrin–expressing CD4+ T cells have a biased central memory phenotype and increased expression of gut-homing molecules
Figure 4. Pathogenicity of βdays after transplantation. Data are from 3 experiments. (1.5 × 10CD4of mice transplanted with B6 Rag-1 BM alone (circles, nwere calculated using the log rank test and 2-tailed Mann-Whitney 2 integrin–expressing CD4+ T cells is
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