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Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis

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Academic year: 2020

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Figure

Figure 1: BMPR1a deletion in mammary carcinomas delays tumor onset and progression. A
Figure 2: BMPR1a deletion in mammary carcinomas results in EMT-like changes. A. Representative image of IHC for the EMT associated transcription factor SNAIL
Figure 3: Microarray analysis of control and BMPR1a deleted tumors. A. Three CTL and three cKO primary whole tumors were analyzed by Affymetrix mouse gene 2.0 DNA microarrays and found to express a set of genes differentially up regulated and down regulate
Figure 4: BMPR1a null primary tumor cell lines have decreased tumorigenicity. A. Total cell counts indicating proliferation rates of control and cKO tumor cells
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