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Tensin4 is up-regulated by EGF-induced ERK1/2 activity and promotes cell proliferation and migration in hepatocellular carcinoma

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Figure

Figure 1: Tensin4 expression in HCC cells. A. Specificity of the Tensin4 specific primers for qPCR assay
Figure 2: SH2 domain was required for the focal adhesion localization of Tensin4. A. Schematic diagram showing the structure of the N-terminal GFP-tagged Tensin4 expression constructs with specific functional domain being removed for the subsequent subcell
Figure 3: EGF-induced Tensin4 up-regulation required ERK1/2 activation followed by transcription- and translation-dependent mechanisms
Figure 4: EGF-induced Tensin4 up-regulation required persistent ERK activation underlying ERK nuclear translocation
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