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B7-H1 and B7-H3 are independent predictors of poor prognosis in patients with non-small cell lung cancer

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Figure

Figure 1: Immunohistochemical staining showing B7-H1 and B7-H3 expression in NSCLC and normal lung tissues (original magnification ×100)
Figure 2: Effects of B7-H3 expression on T-cell proliferation and IFN-γ secretion (1) B7-H3 expression of on cell membrane of H1299
Figure 3: H1299 cell migration induced by IFN-γ after 72 hours. (A) CXCR4 expression by flow cytometry; (B) CXCR4 expression by RT-PCR; (C) Migration ability of H1299 cells before and after IFN-γ stimulation (*p<0.001, compared with all other groups; #p<0.01, compared with the IFN-γ+CXCL12 group) Experiments were done in triplicate and average ± SE displayed.
Figure 4: Migration capacity of H1299-KD and H1299-NC cells H1299-NC cells covered with scratches after 24 hours of incubation, whereas the same phenomena were not observed on H1299-KD cells

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