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Distinct effects of TRAIL on the mitochondrial network in human cancer cells and normal cells: role of plasma membrane depolarization

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Figure

Figure 1: TRAIL modulates the mitochondrial network in melanoma cells. A., B. A375 melanoma cells in FBS/DMEM were plated on a chambered coverglass and treated with soluble recombinant human TRAIL (25, 100 ng/ml) for 24 h A
Figure 2: TRAIL induces mitochondrial fragmentation and clustering in multiple cancer cell lines, but not in normal cells
Figure 3: Mitochondrial fragmentation and clustering are specifically associated with apoptotic cell death
Figure 4A shows the representative blots using A375
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