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Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK

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Academic year: 2020

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Figure

Table 1 Gene primer sequences for RT-PCR analysis
Fig. 1 MA-induced activation of p47phox and MAPKs. Phosphorylation (a) and membrane translocation (b) of p47phox and phosphorylations ofERK (c), p38 (d), and JNK (e) after MA treatment (35 mg/kg, i.p.)
Fig. 2 Effects of U0126 and apocynin or p47phox knockout against MA-induced activations in ERK and p47phox
Fig. 3 Effects of U0126, apocynin, or p47phox knockout on mitochondrial dysfunction after MA treatment
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