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Anti-tumor Effect of Integrin Targeted 177Lu-3PRGD2 and Combined Therapy with Endostar

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Figure

Figure 1. The chemical structure (A) and HPLC chromatography (B) of 177Lu-3PRGD2.
Figure 2. (A) Biodistribution of ratios of 177Lu-3PRGD2 in U87MG tumor-bearing nude mice at 1 h, 4 h, 24 h, and 72 h after injection (370 kBq per mouse)
Figure 3.  Representative planar gamma images of U87MG tumor-bearing nude mice at 4 h and 24 h after intravenous injection of ~74 MBq of 177Lu-3PRGD2
Figure 5.  therapy of established U87MG tumors in nude mice with saline (as control), Endostar (8 mg/kg, peritumoral subcutaneous injection), by an arrow
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