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Quantifying the mapping precision of genome wide association studies using whole genome sequencing data

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Figure

Fig. 1 Differences in MAF between GWAS hits and causal variants for different genotyping strategies
Fig. 2 Mapping precision of GWAS based on different genotyping strategies. Results are from 50,000 simulations for causal common ((within a certain distance as specified on thea) and rareb) variants, respectively, based on the UK10K-WGS data
Fig. 4 Statistical power of GWAS based on different genotyping strategies. Power is calculated as the proportion of simulations with a least avariant at P < 5e-8
Fig. 5 Mapping precision of GWAS based on imputations with different sample sizes of the reference panel
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