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Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver

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Figure

Figure 1Development of NASH-like liver disease as a result of Fbxw7 deletion. (A) Genomic PCR analysis from the mouse liver of the indicated geno-types
Figure 2
Figure 3Deposition of triglyceride and accumulation of SREBP1 in the Fbxw7-deficient liver
Figure 4Increased proliferation and of cyclin E, c-Myc, and Hsp90 (loading control) in liver extracts from Mx150 weeks after by pIpC injection, beginning at 8 weeks of age
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