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MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells

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Figure

Figure 1: Correlations between PKCα expression and Elk-1/MZF-1 expression in breast cancer
Figure 2: Elk-1/MZF-1 complex binds to the promoter region of PKCα to upregulate its protein expression
Figure 3: Identification of MZF-1 and Elk-1 interacting domains. (1–60, 1–72, 1–141, and 60–72) were used to indicate the binding domain of MZF-1 (upper panel)
Figure 4: Disrupting the interaction between Elk-1 and MZF-1 decreases PKCα expression, drug resistance and malignant phenotypes
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